Oxycodone (OP80/OC80)

• May provide significant relief of severe pain when prescribed by a healthcare professional.
• Oxycodone works primarily by activating opioid receptors in the central nervous system to reduce the perception of pain.
• Extended-release formulations may provide longer-lasting pain control when specifically prescribed for appropriate patients.

Take oxycodone exactly as prescribed by your healthcare professional. Follow the instructions for the specific formulation and do not take more than prescribed. If the product is an extended-release tablet, swallow it whole and do not crush, chew, dissolve, or split it unless the product labeling specifically permits this. Never share oxycodone with another person.

• Drowsiness or sleepiness
• Dizziness or lightheadedness
• Nausea or vomiting
• Constipation
• Headache
• Itching or sweating
• Reduced coordination or impaired alertness

Seek emergency medical attention for slowed or difficult breathing, extreme sleepiness, inability to wake, loss of consciousness, blue or gray lips or skin, or suspected overdose.

• Oxycodone is a potent opioid and can cause serious or life-threatening respiratory depression.
• It can cause physical dependence, tolerance, misuse, addiction, and withdrawal symptoms.
• Avoid alcohol and other central nervous system depressants unless specifically approved by your healthcare professional.
• Combining oxycodone with benzodiazepines, other opioids, or certain sedating medicines can substantially increase the risk of profound sedation, respiratory depression, coma, and death.
• Do not drive or operate machinery until you know how the medicine affects you.
• Keep oxycodone securely stored and never give it to anyone for whom it was not prescribed.
• If you have been taking oxycodone regularly, do not stop suddenly without medical guidance because withdrawal symptoms may occur.

Oxycodone can interact with alcohol, benzodiazepines, other opioids, sleeping medicines, sedating antihistamines, muscle relaxants, and other central nervous system depressants, potentially increasing sedation and respiratory-depression risks. Certain medicines that affect liver enzymes, including some CYP3A4 inhibitors or inducers, can also alter oxycodone concentrations. Tell your doctor or pharmacist about all prescription medicines, over-the-counter medicines, vitamins, and supplements you use.

Active ingredient: The active ingredient associated with OP80/OC80 is oxycodone; however, the exact formulation should be confirmed from the original manufacturer's packaging. Some 80 mg oxycodone products are immediate-release while others are extended-release, and inactive ingredients can vary between manufacturers. Do not rely solely on an imprint code to identify an unknown tablet.

Inactive ingredients vary by manufacturer and batch. Check the leaflet inside your pack if you have a known excipient allergy.

Store oxycodone according to the manufacturer's instructions, generally at controlled room temperature and away from excessive heat, moisture, and direct light. Keep the medicine securely stored and out of reach of children, pets, and unauthorized users. Because oxycodone is a controlled opioid medication, follow local guidance for safe storage and disposal of unused or expired medicine.